Concept 4 Review

Tight Junctions

Tight junctions are found predominantly in epithelial tissues, such as intestinal brush border. Water and other fluids must be prevented from leaking between adjacent cells, so that body fluids do not gradually seep across the intestinal lining. In the intestinal lining, tight junctions occur at cell-cell junctions next to the many microvilli that extend into the intestinal space, or lumen, providing increased surface area for adsorption.


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