BioCoach Activity

Concept 3: Krebs Cycle

The Krebs cycle occurs in the mitochondrial matrix and generates a pool of chemical energy (ATP, NADH, and FADH2) from the oxidation of pyruvate, the end product of glycolysis.

Pyruvate is transported into the mitochondria and loses carbon dioxide to form acetyl-CoA, a 2-carbon molecule. When acetyl-CoA is oxidized to carbon dioxide in the Krebs cycle, chemical energy is released and captured in the form of NADH, FADH2, and ATP.

Krebs Cycle