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DNA Structure and Replication
Concept 1: The Nucleotide
   Practice (1 page)
   Review (1 page)
Concept 2: DNA Double Helix
   Practice (1 page)
   Review (2 pages)
Concept 3: Semiconservative Model of DNA Replication    Practice (1 page)
   Review (2 pages)
Concept 4: Biosynthesis of DNA
   Practice (1 page)
   Review (1 page)
Concept 5: Replicating Antiparallel DNA Strands
   Practice (1 page)
   Review (1 page)
Concept 6: Enzymes and Proteins in DNA Replication
   Practice (1 page)
   Review (1 page)
Concept 5: Replicating Antiparallel DNA Strands
The two DNA strands are antiparallel, yet DNA polymerase can only synthesize new DNA in the 5' to 3' direction. This poses special problems for replicating double-stranded DNA.
The double-stranded DNA shown above is unwinding and ready for replication. Note the antiparallel nature of the strands; that is, the 5' to 3' orientation of the top strand and the 3' to 5' orientation of the complementary bottom strand.