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Mendelian Inheritance
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Concept 6: Trait Analysis Short Legs
Concept 6: Trait Analysis: Short Legs 4
Interpreting the Results
F2 Analysis

How is the short-legs trait inherited?

Let us first study the parental cross of the short-legged female with the normal-legged male:

All sons have the same phenotype as the mother and all daughters have the same phenotype as the father.

The simplest hypothesis is that the short-legs trait is caused by an X-linked recessive allele.

Let us go through the crosses with genotypes to see if this could be the case. We will use s for the short-legs allele and S for the normal-legs allele.
If all male offspring of a mutant female and true-breeding normal male have the mutant phenotype and all female offspring have the normal phenotype, the trait is inherited as an X-linked recessive.
Results of the Cross: The F2 Generation