BioCoach Activity

Concept 9: mRNA in Eukaryotes

The sequence of a eukaryotic protein-coding gene is typically not colinear with the translated mRNA; that is, the transcript of the gene is a molecule that must be processed to remove extra sequences (introns) before it is translated into the polypeptide.

Most eukaryotic protein-coding genes contain segments called introns, which break up the amino acid coding sequence into segments called exons.

The transcript of these genes is the pre-mRNA (precursor-mRNA).

The pre-mRNA is processed in the nucleus to remove the introns and splice the exons together into a translatable mRNA. That mRNA exits the nucleus and is translated in the cytoplasm.