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BioCoach Contents
From Gene to Protein: Transcription
Concept 2: Transcription and Translation in Cells
Concept 5: The RNA Molecule
   Review (2 pages)
Concept 6: The Transcription Process
   Practice (1 page)
   Review (3 pages)
Concept 9: mRNA in Eukaryotes
   Review (1 page)
Concept 2: Transcription and Translation in Cells
In a prokaryotic cell, transcription and translation are coupled; that is, translation begins while the mRNA is still being synthesized. In a eukaryotic cell, transcription occurs in the nucleus, and translation occurs in the cytoplasm.
Prokaryotic Cell
Because there is no nucleus to separate the processes of transcription and translation, when bacterial genes are transcribed, their transcripts can immediately be translated.
Eukaryotic Cell
Transcription and translation are spatially and temporally separated in eukaryotic cells; that is, transcription occurs in the nucleus to produce a pre-mRNA molecule.

The pre-mRNA is typically processed to produce the mature mRNA, which exits the nucleus and is translated in the cytoplasm.