LabBench Activity

Some Factors That Affect Enzyme Action

The conformation of an enzyme is maintained by interactions between the various amino acids that compose it, and this conformation is sensitive to changes in the enzyme's environment. Two important influences are pH and temperature. When an enzyme's conformation is significantly altered because of pH or temperature variation, the enzyme may no longer catalyze reactions. An enzyme is said to be denatured when it loses its functional shape.